Dueholm Crews

The present study aims to explore the role of microRNA 145-5p (miR-145-5p) in hyperlipidemia. Using bioinformatics tools and a wide range of function and mechanism assays, we attempted to understand the specific function and potential mechanism of miR-145-5p in hyperlipidemia. A cholesterol-enriched diet induced an increase of serum cholesterol…[Read more]

Hepatoma cells are a promising cell source for the construction of bioartificial liver (BAL) systems owing to their high proliferative capability. However, their low liver function compared with primary hepatocytes is a major problem. In a previous study, we established a genetically modified hepatoma cell line, Hepa/8F5, in which eight…[Read more]

The aqueous extract synthesized using the biomass, Ziziphus spina-christi, was applied to protect the surface of aluminium under acidic environment. The influence of extract concentration (0-0.14 mg/ml), contact time (2-8 h) and temperature (303.15-313.15 K) on the inhibition efficiency was studied. Langmuir isotherm fitted well to the…[Read more]

One in four suicide victims had made at least one prior suicide attempt. The attempt factors related with death by suicide were male gender (HR=2.99; 95% CI, 2.27-3.92), adulthood (over 29 years, HR=2.38; 95% CI, 1.90-2.99), living in a rural area (HR=2.56; 95% CI, 2.04-3.20), chronic disease history (HR=2.43; 95% CI, 1.66-3.57) and depression…[Read more]

While males are more likely diagnosed with cannabis use disorder (CUD), females are more susceptible to developing and maintaining CUD. Yet, for both sexes, CUD is associated with high rates of comorbid mental illness (MI).

To identify and compare sex differences in the prevalence of comorbid CUD amongst individuals with/without…[Read more]

[This corrects the article DOI 10.3389/fpsyg.2021.612030.].The interpersonal communication behaviors of teachers have been substantiated to affect motivation, engagement, and success of students in the academic arena. Aiming to provide a systematic review of some teacher-related constructs in this domain, the present article was a bid to explain…[Read more]

In this physiology-to-bedside review, we provide an updated overview about the role of noninvasive respiratory support strategies as early treatment of hypoxemic respiratory failure in the intensive care unit. Infigratinib nmr Noninvasive strategies appear safe and effective in mild-to-moderate hypoxemia (PaO2/FiO2 > 150 mmHg), while they can yie…[Read more]

5%, while 20-year MFS and CSS in these individuals was reached (64.1% and 60.8%, respectively). Lowest 10-year BCR-free survival (35.6%) was exhibited in pT3b, GGG 4 to 5, R0. Lowest 10-year MFS (49.5%) was exhibited in pT2, GGG 4 to 5, R1. Lowest 10-year CSS (69.8%) was exhibited in pT3b, GGG 4 to 5, R1 patients. In separate pN1 analyses, lowest…[Read more]

Overall, we demonstrate that the dynamics of multiple electrophysiological variables exhibit distinct relationships between their spontaneous and evoked activity, a result which carries implications for experimental design and analysis in non-invasive electrophysiology.

Obesity, one of the most common chronic health conditions worldwide, is a…[Read more]

4 at. % In-SnS2 few layers exhibited an optimal photodetection performance with a high R of 153.8 A/W, a high EQE of 4.72 × 104 %, a great D* of 5.81 × 1012 Jones, and a short response time of 13 ms. Our work provides an efficient path to enhance photodetection performances of photodetectors based on SnS2 for future high-performance o…[Read more]

28, score=3), BP ≥ 130/90 mmHg (2.47, score=1). The AUROC for the model was 0.87, 95% CI, 0.81-0.93 (SE 0.03). A total points score ≥3 represented the best cut-off value, with a sensitivity of 81% and specificity of 82%. CFTRinh-172 inhibitor Across the bootstrapping, the C-statistic for the full screening was 0.86, 95% CI, 0.81-0.93 (SE 0.03).…[Read more]

The development of therapeutic approaches based on direct cardiac reprogramming of fibroblasts into induced-cardiomyocytes (iCM) has emerged as an attractive strategy to repair the injured myocardium. The identification of the mechanisms driving lineage conversion represents a crucial step toward the development of new and more efficient…[Read more]

A series of gold precursor solutions are prepared by dissolving HAuCl4 and its mixtures with K2CO3 of different contents in deionized (DI) water. Neat HAuCl4 predominately forms AuCl4- ions in an aqueous solution. In the presence of K2CO3, AuCl4- ions hydrolyze to form [AuCl4-x(OH)x]- complex ions. Increasing the content of K2CO3 in a gold…[Read more]

hievement. A linear relationship between surgical experience and RC-Pentafecta achievement, without reaching a plateau, was observed.

RC-Pentafecta is a valuable tool to assess surgical quality of RARC and the experience of the center where the surgery is performed and may be used to identify “referral” centers for treatment of high-risk…[Read more]

Radiation therapy is an essential treatment modality for cervical cancer, while accurate and efficient segmentation methods are needed to improve the workflow. In this study, a three-dimensional V-net model is proposed to automatically segment clinical target volume (CTV) and organs at risk (OARs), and to provide prospective guidance for low lose…[Read more]

To evaluate the ciliary body mechanical load during low speed impact using finite element method to explain the mechanism of the cause of angle recession and cyclodialysis cleft.

Optical coherence tomography images were obtained to assess the patient’s ciliary body angle recession. A finite element eye model was established based on…[Read more]

Moreover, MAFF could bind to the promoter region and inhibit the promoter activities of ZO-1, occludin, and claudin-5, which reduced its expression. The combination of RBFOX1 upregulation and LINC00673 downregulation promoted doxorubicin delivery across the blood-tumor barrier, resulting in apoptosis of glioma cells. In conclusion, this study…[Read more]