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679-0.787) for the random forest-trained NEWS parameters only and 0.758 (95% CI, 0.705-0.807) for the random forest-trained NEWS parameters and blood glucose. The models predicted secondary outcomes similarly, but adding blood glucose into the random forest model slightly improved its performance in predicting short-term mortality.

Among unselected prehospital patients, a machine learning model including blood glucose and NEWS parameters had a fair performance in predicting 30-day mortality.

Among unselected prehospital patients, a machine learning model including blood glucose and NEWS parameters had a fair performance in predicting 30-day mortality.

Fast arrival of the cardiac arrest team (CAT) is associated with improved survival after in-hospital cardiac arrest however little is known about how we can minimize delays in CAT arrival. Sulfosuccinimidyl oleate sodium This study aimed to investigate differences in the cardiac arrest call procedures in Danish hospitals and identify causes for adverse events delaying the CAT arrival.

This nationwide study surveyed all public somatic hospitals in Denmark with a CAT. We searched for all patient safety incidences related to the cardiac arrest call procedure during a two-year period. Two researchers reviewed all incidents and categorized the cause as either human, technical, or not possible to classify, and whether the incident caused a delay of the CAT arrival.

In total, 36 hospitals (78%) responded and all hospitals used a telephone number, a CAT activation button or both for activation of the CAT. We found 131 reports describing an event related to activation of the CAT of which 87 incidents (66%) caused a definite delay in CAT arrival. The most common were human errors (43%) followed by technical errors (32%) and errors not possible to classify (25%). Almost half of the incidents (47%) could have been avoided if the hospitals used a CAT activation button with direct activation of the CAT.

There are major differences on the in-hospital cardiac arrest call procedure in Danish hospitals. Human errors are the most frequent cause of safety incidents and may be avoided by simplifying the cardiac arrest call procedure with CAT activation buttons.

There are major differences on the in-hospital cardiac arrest call procedure in Danish hospitals. Human errors are the most frequent cause of safety incidents and may be avoided by simplifying the cardiac arrest call procedure with CAT activation buttons.

To evaluate performance of initial steps of newborn resuscitation according to the American Heart Association and American Academy of Pediatrics’ Neonatal Resuscitation Program (NRP) guidelines in the prehospital setting.

Observational study of 265 paramedics and Emergency Medical Technicians (EMTs) from 45 EMS teams recruited from public fire and private transport agencies in a major metropolitan area. Participants completed a baseline questionnaire assessing demographics, experience, and comfort in caring for children. Simulations were conducted April 2015 to March 2016. Technical performance was evaluated by blinded video review. NRP actions were assessed using a structured performance tool.

Two hundred sixty-five EMS providers responded to survey questions and participated in simulations. In total, 16% reported feeling very or extremely comfortable caring for children <30 days of age (vs. 71% for children aged 12-18 years). Among 45 EMS teams participating in simulations, 22% (n = 10) dried, 18% (n = 8) stimulated, and 2% (n = 1) warmed within 30 s from arrival and 11% (n = 5) provided BMV within 60 s from arrival, as recommended by NRP. All teams provided BMV. Eighty-eight percent bagged below NRP rate recommendations and 96% bagged with tidal volume exceeding guidelines. Looking over the entire 10-min simulation for ever performing measures, 73% started to dry the baby within a median of 51 (range 0-539) seconds from arrival, 38% started to stimulate the baby within a median of 34 s (range 0-181), and 44% started to warm the baby within a median 291 s (range 27-575 s).

These data from field simulations suggest NRP steps recommended for the first minute after birth are seldom performed in a timely manner and suggests opportunities for improvement.

These data from field simulations suggest NRP steps recommended for the first minute after birth are seldom performed in a timely manner and suggests opportunities for improvement.

To estimate the proportion of significant posttraumatic stress (PTS) in both cardiac survivors with good neurologic recovery and informal caregivers, and to pilot test the hypothesis that greater PTS are associated with worse quality of life (QoL) in both cardiac arrest survivors and informal caregivers of cardiac arrest survivors.

We distributed an online survey to survivor and caregiver members of the Sudden Cardiac Arrest Foundation. Participants provided demographic and cardiac arrest characteristics and completed the PTSD Checklist-5 (PCL-5), the Lawton Instrumental Activities of Daily Living scale, and the WHOQOL-BREF. We identified covariates through bivariate correlations or linear regressions as appropriate. Six multiple regression models (three each for survivors and caregivers) examined associations between PCL-5 scores with each QoL subscale, adjusted for covariates identified from the bivariate models.

We included 169 survivors (mean months since arrest 62.8, positive PTS screen 24.9%) and 52 caregivers (mean months since arrest 43.2, positive PTS screen 34.6%). For survivors, the following showed significant bivariate associations with QoL Lawton scores, daily memory problems, sex, months since arrest, age, and income; for caregivers, months since arrest, age, and income. In adjusted models, greater PCL-5 scores were associated with worse QoL (β -0.35 to -0.53, p < .05).

Our pilot results suggest that PTS are prevalent years after the initial cardiac arrest and are associated with worse QoL in survivors and informal caregivers. Further study is needed to validate these findings in a larger, representative sample.

Our pilot results suggest that PTS are prevalent years after the initial cardiac arrest and are associated with worse QoL in survivors and informal caregivers. Further study is needed to validate these findings in a larger, representative sample.

We evaluated the effect of sex and age on out-of-hospital cardiac arrest (OHCA) outcomes in a Canadian population.

This study was a retrospective analysis of the British Columbia (BC) Cardiac Arrest Registry (2011-16). We included adult, non-traumatic, EMS-treated OHCA. We stratified the cohort into four groups by age and sex younger females (18-47 years of age), younger males (18-47 years of age), older females, and older males (>53 years old). We used logistic regression to examine the effect of sex and interaction effect of sex and age on ROSC and survival to hospital discharge.

We included 8115 patients; 31.4% were females. Females had a lower proportion of OHCA in public locations, bystander witnessed arrests, and with initial shockable rhythms. Overall, females had greater adjusted odds of ROSC (OR 1.29, 95% CI 1.15-1.42, p < 0.001). The ROSC advantage was significant in females with non-shockable rhythms (OR 1.48, 95% CI 1.24-1.78, p < 0.001) and females of premenopausal age. However, there was no significant difference in survival to hospital discharge between females and males overall or by sex-age groups. Both younger females and younger males have higher odds of survival to hospital discharge compared to older females and males. Older females had the lowest survival rate among all other sex-age groups.

Female sex was associated with ROSC but not survival to hospital discharge. In the post-arrest phase, females, specifically those in the older age group, had a higher death rate, demonstrating the need for sex- and age-specific research in pre-and-post-OHCA care.

Female sex was associated with ROSC but not survival to hospital discharge. In the post-arrest phase, females, specifically those in the older age group, had a higher death rate, demonstrating the need for sex- and age-specific research in pre-and-post-OHCA care.Cardiac arrest is an important public health concern, affecting an estimated 356,500 people in the out-of-hospital setting and 209,000 people in the in-hospital setting each year. The causes of cardiac arrest include acute coronary syndromes, pulmonary embolism, dyskalemia, respiratory failure, hypovolemia, sepsis, and poisoning among many others. In order to tackle the enormous issue of high mortality among sufferers of cardiac arrest, ongoing research has been seeking improved treatment protocols and novel therapies. One of the mechanical devices that has been increasingly utilized for cardiac arrest is venoarterial extracorporeal membrane oxygenation (VA-ECMO). Presently there is only one published randomized controlled trial examining the use of VA-ECMO as part of cardiopulmonary resuscitation (CPR), a process referred to as extracorporeal cardiopulmonary resuscitation (ECPR). Recently there has been significant progress in providing ECPR for refractory cardiac arrest patients. This narrative review seeks to outline the use of ECPR for both in-hospital and out-of-hospital cardiac arrest, as well as provide information on the expected outcomes associated with its use.

To investigate whether real-time ventilation feedback would improve provider adherence to ventilation guidelines.

Non-blinded randomised controlled simulation trial.

One Emergency Medical Service trust in Copenhagen.

32 ambulance crews consisting of 64 on-duty basic or advanced life support paramedics from Copenhagen Emergency Medical Service.

Participant exposure to real-time ventilation feedback during simulated out-of-hospital cardiac arrest.

The primary outcome was ventilation quality, defined as ventilation guideline-adherence to ventilation rate (8-10 bpm) and tidal volume (500-600 ml) delivered simultaneously.

The intervention group performed ventilations in adherence with ventilation guideline recommendations for 75.3% (Interquartile range (IQR) 66.2%-82.9%) of delivered ventilations, compared to 22.1% (IQR 0%-44.0%) provided by the control group. When controlling for participant covariates, adherence to ventilation guidelines was 44.7% higher in participants receiving ventilation feedback. Analysed separately, the intervention group performed a ventilation guideline-compliant rate in 97.4% (IQR 97.1%-100%) of delivered ventilations, versus 66.7% (IQR 40.9%-77.9%) for the control group. For tidal volume compliance, the intervention group reached 77.5% (IQR 64.9%-83.8%) of ventilations within target compared to 53.4% (IQR 8.4%-66.7%) delivered by the control group.

Real-time ventilation feedback increased guideline compliance for both ventilation rate and tidal volume (combined and as individual parameters) in a simulated OHCA setting. Real-time feedback has the potential to improve manual ventilation quality and may allow providers to avoid harmful hyperventilation.

Real-time ventilation feedback increased guideline compliance for both ventilation rate and tidal volume (combined and as individual parameters) in a simulated OHCA setting. Real-time feedback has the potential to improve manual ventilation quality and may allow providers to avoid harmful hyperventilation.