Wren Nicolaisen

A 67-year-old woman was admitted with exertional dyspnea. She had undergone mitral valve replacement with Björk-Shiley prosthetic valve (convexo-concave type) 36 years previously for stenosis and regurgitation in another institute. An echocardiography showed a severe degree of aortic stenosis, and the implanted mitral valve function is normal. We…[Read more]

Appraisal Tool (MMAT) will be independently used by two reviewers to ensure a rigorous study and quality assessment of all included studies. Discussion This scoping review employs a mixed-method approach to map and select relevant literature and summarize and report on young people’s experiences of sexual aggression in the UK. Once the data is…[Read more]

This analysis predicted that Sox2 targeted a large number of ethanol-dysregulated genes. A gene regulatory network analysis showed that many of the dysregulated genes are targeted by multiple transcription factors. Injection of sox2 mRNA partially rescued ethanol-induced gene expression, epiboly and gastrulation defects. Additional studies of this…[Read more]

The data from three high-spatial-resolution satellites-WorldView-2 (WV-2), WorldView-3 (WV-3), and GaoFen-2 (GF-2)-were used to test the methods and verify the robustness of the OSI. The results show that the OSI index performed well regarding both strong and weak shadows with the user accuracy and the producer accuracy both above 90%, while the…[Read more]

Lower clearances of isovalerylglycine, tiglylglycine, hippurate, and trimethyluric acid were significantly associated with all-cause mortality after adjustment. CONCLUSIONS We found lower kidney clearances of endogenous secretory solutes to be associated with CKD progression and all-cause mortality, independent of eGFR and albuminuria. This…[Read more]

Tuberculous pericarditis is a severe form of extrapulmonary tuberculosis and is the commonest cause of pericardial effusion in high incidence settings. Mortality ranges between 8 and 34%, and it is the leading cause of pericardial constriction in Africa and Asia. Current understanding of the disease is based on models derived from studies…[Read more]

Introduction The aim of this study was to determine the knowledge, attitudes, and practices of family physicians and pediatricians in regard to adolescent immunization.Methods The study was conducted from March to May 2017. A total of 665 physicians participated. Participants were asked 31 questions about their personal sociodemographic…[Read more]