Larkin Shaffer

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  • Larkin Shaffer posted an update 1 day ago

    Upstream analysis determined that the ERH gene may regulate TNF and NK-κB in the BC T24 cell lines. The ERH gene may be involved in the “cell death and survival” molecular network in BC T24 cells. ERH may be a regulator of KITLG through TNF. CONCLUSIONS The ERH gene may affect apoptosis through the TLR, NF-κB, TNF or TGF-beta signalling pathways i…[Read more]

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  • Larkin Shaffer posted an update 2 days ago

    This work is a typical demonstration of setting up a bridge between theory and experiment to give a promising way to the rational design of advanced photocatalysts and atomic understanding of the reaction mechanism. Ethylene response factors (ERFs) are involved in the regulation of plant responses to biotic and abiotic stresses. Here we provide…[Read more]

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  • © FEMS 2020.A combination of favipiravir and zanamivir successfully cleared influenza B infection in a child who had undergone bone marrow transplant for X-linked severe combined immunodeficiency, with no recovery of T lymphocytes. Deep sequencing of viral samples illuminated the within-host dynamics of infection, demonstrating the effectiveness…[Read more]

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  • Multiple myeloma (MM) is a neoplastic dyscrasia of monoclonal immunoglobulin-secreting plasma cells culminating in multi-organ dysfunction. In this study, we sought to investigate whether scutellarin (STN), a flavonoid, could reduce MM progression, mitigate chemoresistance of MM cells to bortezomib (BTB), and cause MM cell apoptosis in a xenograft…[Read more]

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