Temple Flood

Knockdown of the bitter taste receptors mTas2r108, mTas2r137, and mTas2r138 in STC-1 cells by siRNA did could not affect the role of Mat in regulating GLP-1. However, the secretion of GLP-1 by Mat could be significantly inhibited by administration of a CaSR inhibitor or siRNA CaSR. Molecular docking analysis showed that Mat could embed CaSR…[Read more]

013 days and decrease in the DPR by 1.89%, respectively. Increase in milk yield led to increase in FTSS. However, for each 100 kg increase in fat yield and 1% increase in AFP, there is increase in DPR by 0.08% and 0.051%, respectively. Based on the present findings, it may be recommended to have a breeding programme which give due weightage to…[Read more]

Neuroendocrine adrenal chromaffin cells release neurohormones catecholamines in response to Ca2+ entry via voltage-gated Ca2+ channels (VGCCs). Adrenal chromaffin cells also express non-voltage-gated channels, which may conduct Ca2+ at negative membrane potentials, whose role in regulation of exocytosis is poorly understood. We explored how…[Read more]