Mcdonald Vedel

Host-specific natural enemies limit the abundance of common species. This can increase host community diversity, since no single species dominates, and is known as the ‘Janzen-Connell effect.’ Evidence is now accumulating that host-specific mutualists can increase abundances of particular host species, hence reducing community diversity,…[Read more]

QYDP reduced the renal Wnt1, catenin β1, Tgfb1, and Smad2 gene expression and β-catenin, TGF-β, Smad2, collagen I, α-smooth muscle actin, and fibronectin protein expression in diabetic rats. Our results provide the first evidence that QYDP performs its renal-protective function by inhibiting the Wnt/β-catenin and TGF-β/Smad2 signaling pathw…[Read more]

overall health status of the elderly population. However, large-scale clinical studies are needed to confirm our statements.

Localized prostate cancers (PCs) may resist neoadjuvant androgen receptor (AR)-targeted therapies as a result of persistent intraprostatic androgens arising through upregulation of steroidogenic enzymes. Therefore, we…[Read more]

Decreased PD-1 mRNA expression in tumor tissue was associated with poor overall survival (OS). PD-1 mRNA expression in PB of BC patients was higher than that of healthy volunteers, and increased PD-1 mRNA expression in PB was associated with poor OS. FCM revealed that PD-1 was mostly expressed on T cells in PB, predominantly in CD4+ T cells. PD-1…[Read more]

Moreover, distinct urinary volatile profiles were found among patients diagnosed at different tumor stages (Ta/Tis, T1 and ≥T2). This work identified distinct urinary volatile signatures of BC patients with potential for non-invasive detection and staging of bladder cancer.Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis (Mtb) i…[Read more]