MacKay Dunlap

We assumed that the effect of adjuvant trastuzumab on survival is mediated by the treatment time and we conducted this trial-level meta-regression to determine the appropriate length of treatment. Twelve adjuvant trastuzumab trials (from January 2000 to June 2019, consisting of 20,271 patients) were included. We considered 12-month trastuzumab…[Read more]

oleoresins may represent a future source for the discovery of new antimycobacterial drugs due to their low MIC values.Albert Roger Milla speaks to Joseph Martin, Managing Editor Milla is a former international football player for the Cameroon national team. More recently he is the president of the Noma Fund, an association aiming to completely…[Read more]

Weight fluctuations are common among individuals with obesity and are associated with increased morbidity. We examined adipose tissue immune and inflammatory markers in mice following weight loss and partial weight regain. Male C57BL/6 mice were randomized into four groups (n = 8-10/group) low-fat diet for 32 wk (LFD), high-fat diet for 32 wk…[Read more]