Topp McMahan

Hepatocellular carcinoma (HCC) is a malignant tumor with a fairly poor prognosis (5-year survival of less than 50%). Using sorafenib, the only food and drug administration (FDA)-approved drug, HCC cannot be effectively treated; it can only be controlled at most for a couple of months. There is a great need to develop efficacious treatment against…[Read more]

We extend the recently developed generalized Floquet theory [Phys. Rev. Lett. 110, 170602 (2013)] to systems with infinite memory, i.e., a dependence on the whole previous history. In particular, we show that a lower asymptotic bound exists for the Floquet exponents associated to such cases. As examples, we analyze the cases of an ideal 1D system,…[Read more]

This study was aimed at preparing and characterising kojic acid nanostructured lipid carriers (KA-NLCs) for delivery to skin. KA-NLCs were prepared using high-speed homogenization followed by ultra-probe sonication method. KA-NLCs were optimized by glyceryl mono-stearate (GMS) and cholesterol (Chol) as solid lipid excipients, oleic acid (OA) as…[Read more]