McFadden Rooney

Tisagenlecleucel (tisa-cel) is a second-generation autologous CD19-targeted chimeric antigen receptor (CAR) T-cell therapy approved for relapsed/refractory (R/R) large B-cell lymphoma (LBCL). The approval was based on the results of phase II JULIET trial, with a best overall response rate (ORR) and complete response (CR) rate in infused patients…[Read more]

Globally, the conditions and time scales underlying coastal ecosystem recovery following disturbance remain poorly understood, and post-disturbance examples of resilience based on long-term studies are particularly rare. Here, we documented the recovery of a marine foundation species (turtlegrass) following a hypersalinity-associated die-off in…[Read more]

In order to study the degradation laws and mechanisms of admixture concretes with single-added SO42- and composite of Mg2+ and SO42-, respectively, the durability tests were conducted on three types of mineral admixture concretes (concretes with single-added metakaolin (MK), single-added ultra-fine fly ash (UFA), and composite of metakaolin and…[Read more]

Language can influence cognition in domains as varied as temporal processing, spatial categorization, and color perception (Casasanto & Boroditsky, 2008; Levinson & Wilkins, 2006; Winawer et al., 2007). Here, we provide converging behavioral and neural evidence that bilingual experience can change semantic associations. In Experiment 1, Spanish-…[Read more]