Donnelly Tonnesen

  • ApoM-bound S1P decreased PV1 but increased occludin and β-catenin expression in LPS-treated RIMECs. Berberine in a dose-dependent manner raised hepatic ApoM mRNA and plasma ApoM level, but decreased septic hyperglycemia, insulin resistance and plasma TNF-α and IL-1β levels. Berberine reduced sepsis-induced PEPCK and TLR4 mRNA overexpression in th…[Read more]

  • Here, we present elegant examples of a precise determination of the pathways for proton transport.We present for the first time a method for the preparation of magnetic halloysite nanotubes (HNT) by loading of preformed superparamagnetic magnetite nanoparticles (SPION) of diameter size ∼6 nm with a hydrodynamic diameter of ∼10 nm into HNT. We fou…[Read more]

  • Results show that the proposed method is more robust to salt-and-pepper noise and acquires better segmentation results on uneven illumination images in general without compromising its performance on regular illumination images. For a test group of seven real world uneven illumination images, the proposed method could lower the ME value by 15% and…[Read more]

  • Clinical adoption of genomic medicine has lagged behind the pace of scientific discovery. Practice-based resources can help overcome implementation challenges.

    In 2015, the IGNITE (Implementing GeNomics In pracTicE) Network created an online genomic medicine implementation resource toolbox that was expanded in 2017 to incorporate the…[Read more]

  • Acoustic sensors are increasingly used to measure bedload transport in Alpine streams, notably the Swiss plate geophone (SPG) system. CPI-455 nmr An impact experiment using artificial weights is developed in this paper to assess the variability in individual plate response and to evaluate the extent to which calibration coefficients can be…[Read more]

  • Delays in chemotherapy due to missed-appointments can lead to sub-optimal outcomes in any cancer. Missed appointments or delayed follow up are an important concern in the treatment of pediatric cancers as it compromises the patient’s health and overall outcomes.

    This study was conducted to understand the reasons responsible for…[Read more]

  • Donnelly Tonnesen posted an update 2 weeks ago

    The proposed approach deeply checked for their capability of prediction using cognitive scores and EEG measures. The highest accuracies obtained by k NN with 10-fold cross-validation for dementia, early dementia and healthy are 92.00%, 91.67% and 91.87%, respectively.

    The essential findings of this study are 1) Experimental results…[Read more]

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    Most people with opioid use disorder (OUD) are not treated with FDA-approved medications methadone, buprenorphine, or naltrexone. Expanding capacity for evidence-based OUD medication in primary care is a national priority. No studies have examined primary care trainee physicians’ attitudes about these medications. This study surveyed a…[Read more]

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