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ariation in prehospital care exists for patients after TBI in Europe, which is only partially explained by patient factors.

Hypoxia and hypotension continue to occur in patients who suffer a TBI, and remain relatively common in severe TBI. Substantial variation in prehospital care exists for patients after TBI in Europe, which is only partially explained by patient factors.54 children with anisometropic amblyopia of ages 4-15 years were included in the study – 24 children in the patching and 30 children in the MFBF group. The study ran for a period of 6 months with BCVA assessed at each visit of follow up.In the patching group, visual acuity (VA) gain was 0.37 ± 0.26 log Mar over the course of 6 months with continuous improvement in vision across the three time points (0.20 log mar in the first month, 0.11 log Mar from month1 to 3 and 0.06 log Mar from months 3 to 6).In the Amb I Net group, visual acuity gain was 0.54 ± 0.38 log Mar over the same course of time. A continuous improvement in vision was also noted, with gains of 0.16 in the first month, 0.19 from month 1 to 3 and 0.19 from month 3 to 6. The difference in log Mar gains in VA was not statistically significant between the treatment arms and the final VA was similar (0.25 log Mar for patching and 0.18 log Mar for Amb I net). However, clinically the patching group showed 3 log MAR lines, whereas the MFBF group showed 5 log MAR lines of vision improvement at the end of therapy.MFBF was not superior to patching as far as efficacy is concerned in anisometropic amblyopia. However, the combination of more game options to sustain interest, a shorter duration of therapy over the course of a week and software directed compliance monitoring system favors the Amb I Net system from both patient and parental perspective. Amb I Net also negated discomfort, social stigma, and parental monitoring needed with patching regimens. It can be considered as a good alternative to patching in reluctant/non – compliant children with anisometropic amblyopia. This is the first large cohort study based on this therapy.Equinus and toe walking are common locomotor disorders in children with cerebral palsy (CP) walking barefoot or with normal shoes. We hypothesized that, regardless of the type of footwear, the plantar flexors do not cause early equinus upon initial foot contact but decelerate ankle dorsiflexion during weight acceptance (WA). This latter action promoted by early flat-foot contact is hypothesized to be functional. Hence, we performed an instrumented gait analysis of 12 children with CP (Gross Motor Function Classification System class I or II; mean age 7.2 yr) and 11 age-matched typically developing children. The participants walked either barefoot, with unmodified footwear (4° positive-heel shoes), or with 10° negative-heel shoes (NHSs). In both groups, wearing NHSs was associated with greater ankle dorsiflexion upon initial foot contact, and greater tibialis anterior activity (but no difference in soleus activity) during the swing phase. However, the footwear condition did not influence the direction and amplpromoted by early flattening of the foot, and regardless of the type of footwear) may have a functional role.Problem Think-pair-share (TPS) is a teaching strategy that promotes active and collaborative learning; however, the effectiveness and applicability of this strategy in its original or altered form remain to be established, especially in health professions education. As a first step in this direction, the objective of our study was to examine the perceived effectiveness and applicability of TPS including storytelling (TPS-S) in an oral pathology seminar from the perspectives of students, seminar instructors, and peer instructors (experienced instructors who observed the seminar). Intervention Prompts for individual thinking (T), pair discussion (P), and class sharing (S) included clinical case-based questions related to diagnosis and management and wildcards with additional information about the cases. In addition to the traditional TPS phases, the experiences of the leading instructor in dealing with the cases discussed in the seminar were shared through storytelling to model good practices in clinical diagnoitions that facilitated the implementation of TPS-S included the use of real-life clinical cases, instructor facilitation skills, and the scaffolded structure of the seminar. Perceived conditions that hindered the implementation of TPS-S included unequal participation of Y3 and Y4 students, time constraints, and issues related to student pairing. Lessons learned TPS-S was perceived as effective to improve clinical learning and applicable to dental clinical education as long as its implementation matches the characteristics of the learning context. Further evidence is needed to empirically demonstrate the effectiveness and applicability of TPS-S.The objective of the present study was to evaluate the effects of extensive grazingin a sown pasture with forestland on the health of beef cows by measuring multiple indicators. Ten Japanese Black beef cows were used in this experiment. Five of the ten cows were grazed for two months on a 1.8 ha field. The remaining cows were fed under confinement conditions. Behavioral assessments showed that grazing increased sternum lying with rumination of the cows. The grazing cows did not show any abnormal behaviors. There was a tendency for the numbers of red blood cells and lymphocytes to be lower in grazing cows than in confined cows, whereas the number of neutrophils in grazing cows was significantly higher than that in confined cows. In addition, grazing cows had a higher total antioxidant capacity and glutathione peroxidase activity than confined cows. These results suggest that extensive grazing in a sown pasture with forestland increases natural behaviors, decreases circulating red blood cells and lymphocytes and enhances neutrophil circulation, antioxidant enzyme activity, and antioxidant capacity.

Polytrauma (PT) is a leading cause of morbidity and mortality worldwide. However, it is unknown if PT teaching is taught or adequately included in undergraduate medical curricula. We conducted this scoping review to explore the literature on undergraduate PT training.

Using Arksey and O’Malley’s five stage framework, a scoping review was conducted. Nine medical and educational databases, including PubMed, MEDLINE, Scopus, CINAHL, PsycINFO, and EMBASE were searched using keywords identified by the authors. Eligible studies were limited to the English language, with no set limitations on the year of publication. Studies reporting on PT teaching in undergraduate medical curricula were included.

Nine studies were included. The articles were sub-categorised into three themes current teaching of PT in medical curricula, trauma management courses and simulation-based trauma education. Four out of five studies on PT teaching in the curriculum were rated as inadequate by current or past students; on the other hand, three out of four trauma management/simulation courses were evaluated and all three were rated positively by students. Three trauma management courses compared students pre- and post-course scores on a written or practical test and reported significant improvement in post-course scores.

There is a relative paucity of literature on undergraduate PT training. There is a need for more research to explore how to deliver effective PT teaching to medical students.

There is a relative paucity of literature on undergraduate PT training. There is a need for more research to explore how to deliver effective PT teaching to medical students.Metal oxide nanoparticles (MO-NPs) have unique structural characteristics, exceptionally high surface area, strong mechanical stability, catalytic activities, and are biocompatible. Consequently, MO-NPs have recently attracted considerable interest in the field of imaging-guided therapeutic and biosensing applications. This study aims to develop Quantitative Structure-Activity Relationships (QSAR) for the prediction of cell viability of MO-NPs. The QSAR model based on the so-called optimal descriptors which calculated with a simplified molecular input-line entry system (SMILES). The Monte Carlo technique applied to calculate correlation weights for SMILES fragments. Factually, the optimal descriptor for SMILES is the summation of the correlation weights. The model of cytotoxicity is one variable correlation between cytotoxicity and the above optimal descriptor. The Correlation Intensity Index (CII) is a possible criterion of the predictive potential of the model. Applying the CII as a component of the target function in the Monte Carlo optimization routine, employed by the CORAL program, that is designed to find a predictive relationship between the optimal descriptor and cytotoxicity of MO-NPs, improves the statistical quality of the model. The significance of different eclectic features, in terms of whether they increase/decrease cell viability, i.e. decrease or increase cytotoxicity, is also discussed. Numerical data on 83 experimental samples of MO-NPs activity under different conditions taken from the literature are applied for the “nano-QSAR” analysis.

Comparing depression, anxiety, stress and psychopathological symptomatology in pregnancy vs. post-partum in men and in women, marital partners’ (men vs. women) in pregnancy and in post-partum.

During perinatal period, couples undergo emotional changes and psychopathological symptoms.

Descriptive-correlational-longitudinal study. Participants Couples (n = 67; men and women = 134) interviewed in pregnancy and at 8 months post-partum. Women are younger and more educated than men. For 65.7% of couples, this was the first pregnancy.

Sociodemographic and Clinical Questionnaire; Depression Anxiety and Stress Scale-42; Brief Symptoms Inventory.

In pregnancy, women’s scores were significantly higher than men’s in anxiety and somatization. In post-natal period, women presented significantly higher scores in somatization. Between pre- and post-natal periods, women’s scores (stress, obsessions-compulsions, interpersonal sensitivity, depression, hostility, paranoid ideation, psychoticism, global severity index, positive symptoms distress index) rose significantly. Men’s positive symptoms distress index rose significantly.

In pregnancy, women show less stress and less psychopathological symptoms than in post-natal period. During pregnancy women are more anxious and somatise more than men. After birth, they keep somatising more. Also, in perinatal period, women’s changes are more salient. The association of conjugality and motherhood-fatherhood development should be deepened in future investigation.

In pregnancy, women show less stress and less psychopathological symptoms than in post-natal period. During pregnancy women are more anxious and somatise more than men. After birth, they keep somatising more. Also, in perinatal period, women’s changes are more salient. The association of conjugality and motherhood-fatherhood development should be deepened in future investigation.Purpose This update will highlight a few of the projects funded by the National Eye Institute (NEI) Audacious Goals Initiative for Regenerative Medicine (AGI) and show their potential to advance regenerative medicine strategies and increase our understanding of the pathobiology of retinal disease. Methods We summarize the recent updates from a talk given to the scientific community about the progress of various AGI-funded projects. Results NEI is catalyzing the translation of ocular stem cell therapies with its AGI program. Since 2015, NEI has organized 3 consortia to catalyze stem cell-based therapies. The first focuses on developing functional imaging technologies that can enable noninvasive in vivo monitoring of activity of individual retinal neurons. The second consortium is identifying novel neural regeneration factors in the visual system. read more The third, funded in September of 2018, aims to generate translation-enabling models that mimic human eye disease and will evaluate the survival and integration of regenerated neurons in the visual system.