Reynolds Pearson

The experimental results show that the measured removal function is in good agreement with that obtained by numerical simulation. Compared with the circular polishing trajectory, the random-like Lissajous polishing trajectory can significantly improve the material removal rate, and there are no obvious periodic polishing marks on the workpiece…[Read more]

Immune response, proliferation, migration and angiogenesis are juts a few of cellular events that are regulated by transforming growth factor-β (TGF-β) in cells. A number of studies have documented that TGF-β undergoes abnormal expression in different diseases, e.g., diabetes, cancer, fibrosis, asthma, arthritis, among others. This has led to gr…[Read more]

600-2.236) and people of African descent (OR = 1.415; 95%CI 1.236-1.620), respectively (

<0.01) than in the population group that did not identify as belonging to one of those ethnic-racial groups.

There is an association between ethnic-racial status and type of insurance in the contributory and subsidized health systems in Colombia.…[Read more]

Novel height, weight and body mass index (BMI) references for children in Switzerland reveal an increase in BMI compared to former percentile curves. This trend may be the result of children with parents originating from Southern European countries having a higher risk of being overweight compared to their peers with parents of Swiss origin. We…[Read more]

Mechanistically, we found that roflumilast suppressed the activation of the transcriptional factor AP-1 and NF-κB. Our results suggest that roflumilast might be a potential therapeutic agent for the treatment of RA.Immobilization of enzyme on metal-organic frameworks (MOFs) has drawn increasing interest owing to their many well-recognized…[Read more]

The average score at 1year, 2years, 3years, and 5years were significantly higher compared to the average score at 7years and 10years.

The trend of the MFJS score was found to drastically improve from 3weeks to 6months and peak in 2years after which the score tends to attain a plateau up to 5years following which there is a decline in the…[Read more]

However, CTS-induced signaling occurs at concentrations at least one order of magnitude lower than that of inotropy, which eliminates their well known toxic actions on the heart. The current study adds a novel mechanism that CTS could exert its biased signaling properties through the NKA signal transducer. SIGNIFICANCE STATEMENT Although it is now…[Read more]

Background Previous studies have indicated that both genetic and environmental factors contribute to the risk of congenital talipes equinovarus (CTEV). The COL9A1 gene encodes one of the three alpha chains of type IX collagen, which is a key collagen component of hyaline cartilage. Our study aimed to evaluate the effect of COL9A1 gene…[Read more]

Therefore, there is an intense relationship between the local (autocrine) and systemic (endocrine) effects of PCSK9. Although, PCSK9 has been recognized as a ubiquitously expressed modifier of cellular function and signaling molecules, its physiological role in different organs is not well-understood. The current review summarizes these findings.5…[Read more]

After accounting for the effects of biogeography and land use in our analytical approach, each classification explained a substantially higher amount of community variation with 46% of variation explained by our connectivity-informed classification and 42% explained by our locally informed classification. Classifications differed in their ability…[Read more]

094). EP infants with BPD had higher shift than infants without BPD at 36 wk PMA (p < 0.001) and 44 wk PMA (p = 0.005) but not at 1-year cPNA.

In the absence of lung disease, prematurity per se did not result in reduced gas exchange at 1-year cPNA. We report ongoing, significant improvements in pulmonary gas exchange in all preterm infants…[Read more]