Arildsen Gertsen

We also highlight some of the persisting challenges and the solutions to surmount them, paving the way for progress in the field. Finally, we discuss how the combination of novel modalities with 3DBP can pave the way for new frontiers, like four-dimensional bioprinting (4DBP), to bring customized, stimuli-responsive, and highly effective…[Read more]

All organisms have a stress response system to cope with environmental threats, yet its precise form varies hugely within and across individuals, populations, and species. #link# While the physiological mechanisms are increasingly understood, how stress responses have evolved remains elusive. Here, we show that important insights can be gained…[Read more]

Various anesthetic techniques have been utilized for maxillo-mandibular fixation. We report the case of a patient with bilateral condylar and zygomatic arch fractures who had severe pulmonary dysfunction. The patient was administered bilateral image-guided Gasserian ganglion block through the foramen ovale to achieve surgical anesthesia. The…[Read more]

Our results show the therapeutic potential of priprioca residue as a low-cost antiplasmodial agent.Honey is a natural product with a long use in traditional medicine and is well recognized to regulate different biological events. It is an important source of various biological or pharmacological molecules and, therefore, there is a strong interest…[Read more]

It is now well established that the spin-adapted time-dependent density functional theory [X-TD-DFT; Li and Liu, J. Chem. Phys. 135, 194106 (2011)] for low-lying excited states of open-shell systems has very much the same accuracy as the conventional TD-DFT for low-lying excited states of closed-shell systems. In particular, this has been achieved…[Read more]

Mean follow-up was 4 years. Ten patients underwent IFIS and the remaining 20 underwent RIF. The 2 groups showed no difference in demographics, grade of slip, deformity or presenting symptoms. Of 10 treated with IFIS, the SA reduced by a mean of 10 degrees and C7 sagittal vertical line changed by 31 mm. In the RIF cohort, SA reduced by 16 degrees a…[Read more]

Inflammasomes are supramolecular complexes that play key roles in immune surveillance. This is accomplished by the activation of inflammatory caspases, which leads to the proteolytic maturation of interleukin 1β (IL-1β) and pyroptosis. Here, we show that nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing protein 3 (…[Read more]

The standardized uptake value (SUV) is widely used for quantitative evaluation in oncological FDG-PET but has well-known shortcomings as a measure of the tumor’s glucose consumption. selleck compound (SUR) of tumor SUV and arterial blood SUV (BSUV) possesses an increased prognostic value but requires image-based BSUV determination, typically in…[Read more]

Alzheimer’s disease (AD) poses a significant threat to human life and health. The intraneuronal accumulation of β-amyloid (Aβ) plaques in the brains of AD patients results in neuronal cell death, which is a key factor that triggers multiple changes in the pathogenesis of AD. The inhibition of Aβ-induced neuronal cell death may potentially help in…[Read more]

lorectal cancer, KRAS gene mutation can remarkably affect the survival prognosis and change the composition and abundance of intestinal flora, such as Roseburia, Parabacteroides, Metascardovia, Staphylococcus, and Bacillales, thereby influencing tumor development.

The characteristics, significance and potential cause of positive SARS-CoV-2…[Read more]

The effects of copper (Cu) exposure on growth and physiological characteristics of three genotypes (CN-12, Cim-Sanjeevani and Cim-Arogya) of Artemisia annua L. were elucidated. The plants were grown under naturally illuminated greenhouse conditions and were harvested after physiological maturity (120 days after sowing). Results suggest that 10 mg…[Read more]

Combined with solid phase extraction (SPE) technique, MMOF materials have been widely used in the food pretreatment. This article introduced the new preparation strategies of different MMOF materials, systematically summarizes their applications as SPE adsorbents in the pretreatment of food contaminants and analyzes and prospects their future…[Read more]

The Panel considered that, under the intended conditions of use, the risk of allergic sensitisation and elicitation reactions by dietary exposure cannot be excluded, but the likelihood for this to occur is considered to be low. Overall, the Panel cannot conclude on the safety of the food enzyme isoamylase produced with Dyella sp.The food enzyme…[Read more]

005). Post hoc analysis was used to examine the results between groups. Selleck 2-D08 of group 1 and group 3 were equal (P= 1) and lower than group 2 (P= 0.04 and P= 0.006, respectively).

Lutein was found to have a positive effect on width of the basilar artery lumen area. Therefore, positive effects of lutein on vasospasm might be…[Read more]

Although these compounds may reduce the severity and slow the progression of NDD, research gaps remain in antioxidants supplementation in AD, PD, and ALS patients, which indicates that further human studies applying antioxidant supplementation in different forms of NDDs are urgently needed.A GC-MS/MS method with EI ionization was developed and…[Read more]

Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a high mortality. This study assessed venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for sepsis-induced cardiogenic shock refractory to conventional treatments.

In this retrospective, multicentre, international cohort study, we compared outcomes of…[Read more]

The failure of the market and government to provide quality healthcare services have been the motivation to set up social health enterprise. However, the value for money associated with setting up a social health enterprise in sub-Sahara African countries has been relatively unexplored in the literature. The study presents the first empirical…[Read more]

05). GLUT-4 quantity in the membrane fractions in all groups was more than cytosolic fractions. The amount of GLUT-4 in membrane fraction of treated cells in the presence of PI3K inhibitor was higher than in the cells treated with this extract in the presence of AMPK inhibitor (P-value < 0.05).

Ethyl acetate ginger extract affects the…[Read more]