Site-Wide Activity

We aimed to improve the assessment of the drug activity in meningioma clinical trials based on the study of the 3D volume growth rate (3DVGR) in a series of aggressive meningiomas. We secondarily aimed to correlate 3DVGR study with patient outcome.

We performed a posthoc analysis based on volume data and 3DVGR extracted from CEVOREM study…[Read more]

A flow-controlled microfluidic device for parallel and combinatorial screening of crystalline materials can profoundly impact the discovery and development of active pharmaceutical ingredients and other crystalline materials. While the existing continuous-flow microfluidic devices allow crystals to nucleate under controlled conditions in the…[Read more]

The bleeding phenotype of von Willebrand disease (VWD) varies highly between patients and can only partly be explained by von Willebrand factor (VWF) parameters. By cleaving large VWF multimers into smaller, less active multimers, ADAMTS-13 is an important regulator of VWF activity. However, it is unknown what the role of ADAMTS-13 is in…[Read more]

Also, we present the experimentally measured volt-watt responsivity (S~) within the frequency range ω ≈ (0.3-6) THz VN HEB detector. The estimated values of noise equivalent power (NEP) for VN HEB and its minimum energy level (δE) reached NEP@1MHz ≈ 6.3 × 10-14 W/√Hz and δE ≈ 8.1 × 10-18 J, respectively.This study aimed to validate the Clinica…[Read more]

Novel LG1 Versions inside Agrin Creating Hereditary Myasthenia Symptoms.

OBJECTIVE To explore the expression of Stomatin-like protein 2 (SLP-2) and its clinical significance in epithelial ovarian cancer (EOC). PATIENTS AND METHODS Quantitative real-time polymerase chain reaction (qRT-PCR) was used to detect the differential expression of SLP-2…[Read more]

Objective This study aimed to estimate and investigate the prevalence and the risk factors implicated in contact dermatitis among healthcare workers in the Al’Qassim region, Saudi Arabia, during the COVID-19 pandemic. Kenpaullone cell line Methodology We conducted a cross-sectional survey among healthcare workers at hospitals in the Al’Qassim…[Read more]

4% showed moderate PA and 23.2% a low PA score. A progressive reduction in ADL and IADL score was associated with lower physical activity (p value = 0.0038 and 0.0017). We consider cognitive performance reduction with a cut off of loss of more than 5 points in Short Port of ADL and IADL and a loss of more than 15 points on Exton-Smith Scale,…[Read more]

igm, our theoretical framework remains to be thought-provoking, and hypothesis-generating at the present time. Muscle coordination plays an important role in glenohumeral stability. The rotator cuff and the long head of the biceps are considered the primary dynamic stabilizers muscles. However, the fact that a subgroup of patients with a massive…[Read more]