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Streptomyces genomes harbor numerous, biosynthetic gene clusters (BGCs) encoding for drug-like compounds. While some of these BGCs readily yield expected products, many do not. Biosynthetic crypticity represents a significant hurdle to drug discovery, and the biological mechanisms that underpin it remain poorly understood. Polycyclic tetramate…[Read more]

In today’s interconnected world, the significance of vpn comparison and security can not be overstated. As persons and organizations increasingly depend on the net for transmission, transactions, and information sharing, the need for robust protective methods becomes paramount. One of the most effective tools designed for safeguarding on line…[Read more]

Our social network analysis using the comprehensive ICU interaction data obtained by wearable sensors has revealed the leading roles played by nurses within the professional communication network.

Rural Latino children with asthma suffer high rates of uncontrolled asthma symptoms, emergency department visits, and repeat hospitalizations. This…[Read more]

genous population.Numerous studies demonstrate frequent mutations in the genome of SARS-CoV-2. Our goal was to statistically link mutations to severe disease outcome. We used an automated machine learning approach where 1594 viral genomes with available clinical follow-up data were used as the training set (797 ‘severe’ and 797 ‘mild’). The best…[Read more]

In this meta-analysis we provided two models which both reported a significant increase in the risk of COVID-19 severity and mortality among patients with mental disorders, and with the upcoming COVID-19 vaccines, we recommend to give this category the priority in the vaccination campaigns along with medical health providers and…[Read more]

This study aimed to develop/evaluate the psychometric properties of the Arabic Fonseca Anamnestic Index (FAI-A) and estimate the prevalence of TMDs in prospective orthodontic patients.

The FAI-A was derived by forward-backward translation/cross-cultural adaption of the English FAI. Psychometric assessment of the FAI-A was performed with…[Read more]

One of the main challenges in higher education is promoting students’ autonomous and self-regulated learning, which involves managing their own emotions and learning processes in different contexts and circumstances. Considering that online learning during the COVID-19 pandemic may be an opportunity for university students to take greater…[Read more]

ementation as soon as possible. Early intervention builds on a critical developmental time for plasticity of developing systems. Referrals for intervention across the 9 domains should be specific as per recommendations in this guideline.

When a child meets the criteria of high risk of CP, intervention should start as soon as possible. Parents…[Read more]

This model could be advantageous for the in-depth study of cellular immune responses to the S protein and other viral antigens, such as nucleocapsid and matrix antigen. The S protein appears to be the important viral protein that may be able to mimic the natural infection process intranasally and should be studied as a component of a candidate…[Read more]

Achaiah NC, Subbarajasetty SB, Shetty RM. R

and R

of COVID-19 Can We Predict When the Pandemic Outbreak will be Contained? Indian J Crit Care Med 2020;24(11)1125-1127.

Achaiah NC, Subbarajasetty SB, Shetty RM. R0 and Re of COVID-19 Can We Predict When the Pandemic Outbreak will be Contained? Indian J Crit Care Med…[Read more]