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Multiple myeloma (MM) is a neoplastic dyscrasia of monoclonal immunoglobulin-secreting plasma cells culminating in multi-organ dysfunction. In this study, we sought to investigate whether scutellarin (STN), a flavonoid, could reduce MM progression, mitigate chemoresistance of MM cells to bortezomib (BTB), and cause MM cell apoptosis in a xenograft…[Read more]

es in a.p. view as with conventional radiographs in a.p. view. • EOS can be safely used for primary assessment of osteoarthritis of the knee. • In the preoperative setting for knee replacement surgery, conventional radiographs in two or three planes of the knee should still be acquired in addition to long-leg EOS images.In a previous version of…[Read more]

This has very powerful practical applications for industry leaders, since, with this new approach, they can potentially allow a better understanding of the complex processes underlying the strategic design of organizations and, above all, make decisions in real-time.The impact of adjusted treatment on clinical outcomes in patients with severe…[Read more]

The purpose of this study was to explore the regulatory effect of resveratrol (RES) on lipopolysaccharide (LPS)-induced inflammation and its influence on intestinal microorganisms and serum atlas in murine models during the development of inflammation to explore a novel method for the regulation of inflammation. Mice were randomly assigned to…[Read more]

The occurrence of the latter between 130 and 190 mg/dL was present in 1,643 (17.1%) individuals, and 228 (2.4%) patients had an LDL-cholesterol ≥190mg/dL among those using statins at distinct doses. Only two statins were used simvastatin and atorvastatin. The first was prescribed in 77.6% of the prescriptions.

In this cross-sectional c…[Read more]

Bioswales are best for phosphorus and bacteria removal; both wet swales and bioswales can also treat heavy metals. Selection of a swale type depends on the site constraints, local climate, and available funding for design, construction, and operation. Appropriate siting, pre-design site investigations, and consideration of future maintenance…[Read more]

The sinoatrial node is perhaps one of the most important tissues in the entire body it is the natural pacemaker of the heart, making it responsible for initiating each-and-every normal heartbeat. As such, its activity is heavily controlled, allowing heart rate to rapidly adapt to changes in physiological demand. Control of sinoatrial node…[Read more]

resilient logistics system, strengthen domestic manufacturers’ capabilities, and develop contingency plans with supplying partners.

This survey reveals how Covid-19 has influenced service providers’ logistics systems. Following the pandemic, the line fill rate fell below half with a three-fifths availability of products. To effectively manage…[Read more]

To remedy these gaps, researchers must continue to further elucidate the needs, preferences, and gaps regarding access to early care and education opportunities for Latino children. For those studying trauma and ACEs among low-income children, greater attention to how preventative interventions or treatments that are embedded in ECE settings serve…[Read more]

Household disinfectant and cleaning products (HDCPs) assessment is challenging in epidemiological research. We hypothesized that a newly-developed smartphone application was more objective than questionnaires in assessing HDCPs. Therefore, we aimed to compare both methods, in terms of exposure assessments and respiratory health effects estimates.…[Read more]

05). The IIEF scores of the PLS and DJS groups were 8.44 ± 2.10 vs 12.50 ± 1.78 (P = 0.003) at 2 weeks, 8.65 ± 1.90 vs 13.42 ± 1.88 (P = 0.002) at 4 weeks, and 13.57 ± 1.01 vs 17.38 ± 2.47 (P = 0.003) at 6 weeks after operation, with no statistically significant difference between the two groups at 8 weeks.

Ureteral stenting affects the q…[Read more]

Egg predation was the leading cause of nest failure, followed by haying of the nest bowl and death of the incubating hen. Poults reared by adult hens had a greater probability of survival than poults reared by yearling hens. Our estimate of survival probability of poults raised by yearling hens was low relative to other studies, which may be…[Read more]

In hand-held human machine systems the biodynamic response of the human hand arm system influences the overall dynamic behavior. The biodynamic response of the hand arm system is affected by several influencing factors. These influencing factors include the feed force, body posture, gripping force, and anthropometric properties. In present studies…[Read more]

The first case of a coronavirus 2019 (COVID-19) infection in a Sri Lankan was reported on March 11, 2020. The situation in Sri Lanka changed with the rapid increase of personnel contracting COVID-19 in a naval base camp that housed more than 4000 people. This provided a unique opportunity to study the effectiveness of hydroxychloroquine (HCQ) for…[Read more]