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According to real time (RT)-PCR and three-dimensional (3D) digital (d) PCR analysis, dual RdRP and N1 gene positivity were detected in 20 (9.8%) samples. Ambient PM-bound SARS-CoV-2 was analyzed quantitatively and the air concentrations of the virus ranged from 0.1 copies/m3 to 23 copies/m3. The highest percentages of virus detection on PM samples were from hospital gardens in Tekirdağ, Zonguldak, and Istanbul, especially in PM2.5 mode. Findings of this study have suggested that SARS-CoV-2 may be transported by ambient particles, especially at sites close to the infection hot-spots. However, whether this has an impact on the spread of the virus infection remains to be determined.Due to the high ecological vulnerability of the Pan-Third Pole region and the complexity of its ecological process, the impact of urbanization on the ecological environment (eco-environment) in this specific region attracts global attention. Here, we established an effective framework to evaluate the coupling coordination process of urbanization and eco-environment, and investigated the spatial distribution and dynamic evolution of this coupling coordination. Results showed that the Pan-Third Pole is undergoing an accelerated process of urbanization. Meanwhile, the overall eco-environment has profoundly changed from an ecological reserve to an ecological deficit. The coupling degree between urbanization and eco-environment shows an upward trend, and the decoupling process dynamically changes between various types. Regional convergence is remarkably embodied in the coupling and decoupling types. We found four coupling categories and three decoupling categories for the interaction between urbanization and eco-environment. Among them, the first coupling category contains 35 countries, which maintained a basically coordinated pattern with eco-environment lag. The initial urbanization level of the first category was higher than 35%, indicating that countries with higher urbanization levels were more likely to achieve coordinated development between urbanization and eco-environment. There was a noteworthy “path-dependence” in the evolution of the coordinated relationship between urbanization and eco-environment in the Pan-Third Pole. These findings will have important policy implications for decision-makers to explore coordination and sustainable development path for urbanization and eco-environment conservation.This study investigates the effect of psychrophilic, mesophilic and thermophilic temperatures on the anaerobic treatment of slaughterhouse wastewater, in terms of biogas production, occurrence of 30 pharmaceutical compounds of veterinary use, 4 antibiotic resistance genes (ARGs) which provide resistance to tetracyclines (tetW), fluoroquinolones (qnrS), macrolide-lincosamide-streptogramin (ermB) and sulfonamides (sul1) antibiotics, as well as class I integron-integrase gene (intI1), related to horizontal gene transfer. The highest methane yield was obtained at a mesophilic temperature (35 °C) (323 mL CH4/g TCOD) followed by the yield obtained at thermophilic temperature (53 °C) (242 mL CH4/g TCOD). Regarding pharmaceuticals, chlortetracycline, oxytetracycline, tilmicosin, and lincomycin were the most abundant in the slaughterhouse wastewater, being detected predominantly in the solid phase (with median concentrations >200 μg/kg dry weight). On the other hand, ciprofloxacin, ofloxacin, norfloxacin, lincomycin and ibuprofen were the most predominant in the anaerobic digestate regardless of the treatment temperature. Psychrophilic temperatures (21 °C) exhibited moderate to low pharmaceuticals removal, while a large fraction of them were removed at a thermophilic temperature reaching 70-90% removals for tetracycline, macrolides and one sulfonamide (sulfapyridine). The highest relative abundance of the quantified ARGs was found at 53 °C, suggesting that thermophilic temperatures normally associated with better removals of pathogens do not necessarily show better removals of antibiotic resistance genes.The stomatal traits influence ecosystem carbon-water fluxes and play essential roles that enable plants to adapt to changing environmental conditions. However, how stomatal traits vary along a large climate gradient and whether stomatal traits coordinated with other leaf functional traits in response to environmental changes remain unclear. We investigated the stomatal density (SD), stomatal size (SS), and leaf traits (leaf area (LA), leaf mass per area (LMA), and vein density (VD)) of 44 in situ Quercus variabilis populations across Eastern Asia (24 to 51.8°N, 99 to 137°E) and 15 populations grown in a common garden, and evaluated their relationships with environmental factors. Stepwise multiple regression showed that the SD was significantly associated with mean annual precipitation (MAP), LMA, and VD, and the SS with latitude, mean annual temperature (MAT), mean monthly solar radiation (MMSR), and VD. The SD was positively correlated with the LMA, while the SS was negatively correlated with the VD. SR18662 in vitro The SD and LMA increased with decreasing precipitation, which indicated that they may coordinate to commonly enhance plant resistance against drought. The SS decreased; however, the VD increased with temperature. This implied that plants might further reduce their SS by increasing VD limitations under global warming. In the common garden, plants exhibited a higher SD and VD and lower SS and LA compared to those in the field; however, no relation between the stomatal and leaf traits was observed. Our results suggested that stomatal traits have high environmental plasticity and are highly coordinated with other leaf functional traits in response to environmental changes. Nevertheless, this coordination may have been formed through long-term adaptations, rather than over short time spans.Indoor air purifiers are increasingly marketed for their health benefits, but their cardiovascular effects remain unclear. We systematically reviewed and meta-analysed randomized controlled trials (RCTs) on the cardiovascular effects of indoor air purification interventions in humans of all ages. We searched Embase, Medline, PubMed, and Web of Science from inception to 22 August 2020. Fourteen cross-over RCTs (18 publications) were included. Systolic blood pressure (SBP) was significantly reduced after intervention (-2.28 (95% CI -3.92, -0.64) mmHg). There were tendencies of reductions in diastolic blood pressure (-0.35 [-1.52, 0.83] mmHg), pulse pressure (PP) (-0.86 [-2.07, 0.34] mmHg), C-reactive protein (-0.23 [-0.63, 0.18] mg/L), and improvement in reactive hyperaemia index (RHI) (0.10 [-0.04, 0.24]) after indoor air purification, although the effects were not statistically significant. However, when restricting the analyses to RCTs using physical-type purifiers only, significant improvements in PP (-1.56 [-2.