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018), disease duration <5 years (p = 0.02), not childbearing before MS diagnosis (p < 0.001) and neurologist addressing family planning (p = 0.01) were significantly associated with childbearing desire.

This research highlights that pregnancy remains an important concern among WwMS.

This research highlights that pregnancy remains an important concern among WwMS.Digital Pathology (also referred to as Telepathology and Whole Slide Imaging) is the process of producing high resolution digital images from tissue sections on glass slides. These glass slides are normally examined under a microscope by a pathologist as part of the diagnostic process. The emergence of digital pathology now means that digital images are stored on secure servers and can be viewed on computer monitors; enabling pathologists to work remotely and to collaborate with other colleagues when second opinions are needed. The implementation of digital pathology into clinical practice has many potential benefits. Although this has been long recognised, its adoption as a diagnostic tool remains low and pathologists’ projections about its future deployment are cautious. Notable early digital pathology adopters have led the way. Autophinib The challenge now is to scale-up digital pathology beyond the relatively few large networks and centres of excellence. Many other areas of healthcare have accumulated experience about optimising approaches to digital health/healthcare technology deployment and sustainability. This has been done in a multi-disciplinary context and has applied theoretical/conceptual frameworks. Thus far there has been little use of similar frameworks in the planning of digital pathology deployment in clinical practice. In this essay, I will explore the scope of digital pathology implementation approaches that have been deployed in clinical practice and examine what can be learned from the wider healthcare experience of adopting, scaling-up and sustaining innovative healthcare solutions.The present paper is aimed at understanding the importance of motivation (perceived qualitatively) in ensuring the success of the dietary change process. This study expands on previous research by confronting the perspective of persons dieting to lose weight with the perspective of professionals providing support (dietitians). We interviewed 13 respondents (six patients, seven dietitians) and performed a thematic analysis. The study’s results show that understanding motivational mechanisms is a prerequisite for a consistent narrative in the patient-dietitian dyad. The research results could help in developing effective dietary interventions that could facilitate effective and permanent dietary change.Self-assembled nanoribbons from small molecule amphiphiles with chelating head groups and a structural domain to impart mechanical stability are reported for the remediation of lead from contaminated water. The nanoribbons’ remediation capacity is affected by pH and the presence of competing cations, and can be modulated by head group choice.Thin films of the organic semiconductor Ph-BTBT-10 and blends of this material with polystyrene have been deposited by a solution shearing technique at low (1 mm s-1) and high (10 mm s-1) coating velocities and implemented in organic field-effect transistors. Combined X-ray diffraction and electrical characterisation studies prove that the films coated at low speed are significantly anisotropic. The highest mobility is found along the coating direction, which corresponds to the crystallographic a-axis. In contrast, at high coating speed the films are crystallographically less ordered but with better thin film homogeneity and exhibit isotropic electrical characteristics. Best mobilities are found in films prepared at high coating speeds with the blended semiconductor. This work demonstrates the interplay between the crystal packing and thin film morphology and uniformity and their impact on the device performance.Within the lithium-sulfur (Li-S) battery, a wide variety of soluble lithium polysulfide intermediates form during operation. Under lean-electrolyte or low-temperature conditions, the solution coordination of polysulfides dynamically shifts to highly clustered states, which is subsequently accompanied by inhibited electrochemical kinetics. In fact, it has been shown that the tendency for polysulfides to strongly aggregate is one of the dominant kinetically limiting obstacles towards achieving adequate utilization of active material under such conditions. While this association has been noted before, it is not explicitly understood what mechanism intrinsic to polysulfide clustering curtails the electrochemical utilization of active material, particularly during the conversion to insoluble Li2S. Here, we perform a series of investigations to unify and link the kinetic constraints that arise from polysulfide clustering to the nucleation and growth behavior of Li2S. We find that there is a drastic decrease in polysulfide diffusion coefficient arising from the advent of clustering, and that this decline functionally matches that seen for the nucleation and growth rate constants for Li2S deposition. Additionally, it is found that there is a less favorable minimization of energy during Li2S nucleation, arising from the altered solvation stability of polysulfide clusters. This knowledge expands our understanding of the Li-S materials chemistry and the primary factors dictating the electrochemical behavior.Small saccular aneurysm in the right gastroepiploic artery is a sporadic disease accounting for approximately 0.4% of abdominal visceral aneurysms rarely observed during routine examination of other illnesses; however, it has been reported following rupture. The right gastroepiploic artery is a common alternative to the internal thoracic artery in coronary artery bypass grafting. We report a case of small aneurysms in the left anterior descending artery, diagonal branch artery, and right gastroepiploic artery and a pseudoaneurysm in right gastroepiploic artery. Coronary artery bypass grafting was performed using the left internal thoracic artery and right gastroepiploic artery, and a 5-mm aneurysm was observed in the right gastroepiploic artery. The resected 5-mm right gastroepiploic artery aneurysm was saccular. Pathological investigation revealed media loss and adventitial thinning, indicating the possibility of an aneurysm rupture. Thus, preoperative three-dimensional computed tomography is beneficial for patients with coronary arterial aneurysms and preoperative evaluation of right gastroepiploic artery to help achieve good clinical outcomes in patients undergoing coronary artery bypass grafting with another arterial aneurysm.