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Collins Saunders posted an update 16 hours, 56 minutes ago
Professionals who specialize in breast imaging may be the first to initiate the conversation about genetic counseling with patients who have a diagnosis of premenopausal breast cancer or a strong family history of breast and ovarian cancer. Commercial genetic testing panels have gained popularity and have become more affordable in recent years. Therefore, it is imperative for radiologists to be able to provide counseling and to identify those patients who should be referred for genetic testing. The authors review the process of genetic counseling and the associated screening recommendations for patients at high and moderate risk. Ultimately, genetic test results enable appropriate patient-specific screening, which allows improvement of overall survival by early detection and timely treatment. The authors discuss pretest counseling, which involves the use of various breast cancer risk assessment tools such as the Gail and Tyrer-Cuzick models. The most common high- and moderate-risk gene mutations associated with breast cancer are also reviewed. In addition to BRCA1 and BRCA2, several high-risk genes, including TP53, PTEN, CDH1, and STK11, are discussed. Moderate-risk genes include ATM, CHEK2, and PALB2. The imaging appearances of breast cancer typically associated with each gene mutation, as well as the other associated cancers, are described. ©RSNA, 2020 See discussion on this article by Butler (pp XXX-XXX).US-guided foreign body removal is a nonsurgical highly effective technique used to manage symptomatic foreign bodies and should be considered as a first-line treatment procedure. The authors describe a technique used for US detection and US-guided removal of various types of foreign bodies and discuss the efficacy of the procedure. Soft-tissue foreign bodies can result from accidents or medical procedures, and they are a relatively frequent reason that patients obtain medical consultation. Foreign body objects include vegetal, metallic, and glass objects, and they may be medical devices such as contraceptive implants. Frequently, physical examination is not sensitive enough to detect the presence of a foreign body, and imaging is necessary. US has demonstrated high specificity and moderate sensitivity for detection of foreign bodies, and it has the advantage of depicting all types of materials. Thus, US has become the imaging technique of choice for evaluating suspected foreign bodies. Although the US features are dependent on the foreign body type and shape, all foreign bodies are echogenic and frequently demonstrate posterior shadowing or reverberation artifact. US has an added value in that it can be used to plan the removal of a foreign body and also guide the entire percutaneous removal procedure. Through a small incision in the skin, just wide enough for the foreign body to pass through, surgical forceps can be inserted and directed under US guidance to reach the foreign body and remove it. see more The effectiveness of US-guided percutaneous removal can be near 100%. Online supplemental material is available for this article. ©RSNA, 2020.Objectives To examine three different methods for evaluating the effect of percutaneous sclerotherapy on limb venous malformations in a series of patients with a relatively long follow-up. Method The study was a retrospective study. Results Thirty-eight patients treated with percutaneous sclerotherapy underwent sclerotherapy, with a median number of sessions of 4 (range, 1-10). They were followed up for 1-60 months (average 12.5 months). The kappa between clinical manifestations and Doppler ultrasound was 0.684 (P less then 0.001). The kappa between clinical manifestations and magnetic resonance imaging was 0.217 (P = 0.006). The kappa between Doppler ultrasound and magnetic resonance imaging was 0.323 (P less then 0.001). The rate of grade IV patients evaluated by clinical manifestations was significantly higher than that by Doppler ultrasound and magnetic resonance imaging. Conclusions Magnetic resonance imaging is the gold standard for VM imaging. Its consistency with clinical examination and Doppler ultrasound is poor, and Doppler ultrasound and clinical examination could be more appropriate for follow-up imaging after sclerotherapy.We investigated the psychometric properties of the Fear of COVID-19 Scale in Turkish among a diverse group with a focus on the prevalence of coronavirus related fear across gender, age intervals, SES, chronic illness situation, and educational level. Based on a confirmatory factor analysis, the Fear of COVID-19 Scale had appropriate psychometric properties for utilization, including excellent goodness-of-fit indices, a Cronbach’s alpha value of .86, and discriminant validity, as shown by a significant negative correlation with resilience. Furthermore, group comparison analyses revealed that women reported significantly higher fear of coronavirus. Additionally, individuals from middle SES reported significantly higher fear of coronavirus while the fear of coronavirus did not differ based on participants’ educational level, socioeconomic status, and age level. Implications for mental health providers are discussed.Purpose Bladder-bowel questionnaires (BBQ) are an important tool in diagnosing non-neurogenic bladder-bowel dysfunction (BBD) in children. In this study, we report the validity and reliability of a BBQ, which has been in clinical use in our institution for decades. Material and methods The BBQ contains 13 questions with answers ranging from never (0) to daily3. It was answered by 139 healthy controls and 134 children aged 3-16 years diagnosed with BBD by a pediatric urologist/urotherapist. A sub-diagnosis, of overactive bladder (OAB) or dysfunctional voiding (DV), was given each patient. BBQ scales were developed and evaluated against hypotheses of validity (known-groups/convergent/discriminating) and reliability (internal consistency/retest reliability), sensitivity and specificity. Responsiveness was tested in 80 patients who answered the BBQ after treatment. Results A total BBD score scale demonstrated ability to discriminate between patients with a BBD and healthy subjects. It resulted in a ROC curve with AUC 0.