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Acute infarction patterns have been described in cardioembolic stroke, mainly with atrial fibrillation (AF) or patent foramen ovale. We aimed to analyse acute infarction magnetic resonance imaging (MRI) characteristics in stroke patients with intracardiac thrombus (ICT) compared with stroke patients with AF.

We performed a retrospective study analysing brain MRI scans of consecutive acute symptomatic cardioembolic infarction patients associated with ICT or AF who were recruited and registered in the stroke database between June 2018 and November 2019. Diffusion-weighted imaging performed within 1 week after symptom onset, intra-/extracranial vessel imaging, echocardiography, and ≥24-h ECG monitoring were required for inclusion. Baseline, biological, and echocardiography characteristics were assessed. Analysed MRI characteristics were infarction location (anterior/middle/posterior cerebral artery territory; anterior/posterior/mixed anterior-posterior circulation; multiterritorial infarction; brainstem; cerd for SCCI (more frequent in the ICT group, p = 0.053) and non-SCCI (more frequent in the AF group, p = 0.053) on MRI.

ICT-related stroke is associated with acute SCCI presence on MRI. Clinical Trial Registration-URL http//www.clinicaltrials.gov. KU-0063794 Unique identifier NCT04456309.

ICT-related stroke is associated with acute SCCI presence on MRI. Clinical Trial Registration-URL http//www.clinicaltrials.gov. Unique identifier NCT04456309.

Dementia is a chronic disease with a variable prevalence throughout the world; however, this could be higher at high-altitude populations. We aimed to summarize the prevalence of cognitive impairment and dementia in older adults living at high altitude.

We searched in PubMed, Medline, Scopus, Web of Science, and Embase and included the studies published from inception to July 20, 2020, with no language restriction, which reported the frequency of cognitive impairment or dementia in older adults living at high-altitude populations. Random-effects meta-analyses were performed to calculate the overall prevalence and 95% confidence intervals (95% CI) of cognitive impairment and dementia. The risk of bias was evaluated using the Newcastle-Ottawa Scale (NOS) adapted for cross-sectional studies.

Six studies were included (3,724 participants), and 5 of the 6 included studies were carried out in Latin America. The altitude ranged from 1,783 to 3,847 m, the proportion of women included varied from 38.7 to 65.6%, and the proportion of participants with elementary or illiterate educational level ranged from 71.7 to 97.6%. The overall prevalence of cognitive impairment was 22.0% (95% CI 8-40, I2 99%), and the overall prevalence of dementia was 11.0% (95% CI 6-17, I2 92%). In a subgroup analysis according to the instrument used to evaluate cognitive impairment, the prevalence of cognitive impairment was 21.0% (95% CI 5-42, I2 99%) in the MMSE group while the prevalence was 29.0% (95% CI 0-78) in the non-MMSE group.

The prevalence of cognitive impairment and dementia in older adults living at high altitude is almost twice the number reported in some world regions.

The prevalence of cognitive impairment and dementia in older adults living at high altitude is almost twice the number reported in some world regions.The goal of this report is to recount the history of the International Society for Research in Human Milk and Lactation (ISRHML) and how its members contributed to the science of human milk (HM) and lactation (LT). The ISRHML was formed in 1988 by a group of young scientists who were intrigued with the mysteries of HM and LT and the effects of HM upon recipient human infants. The inception of the ISRHML by those scientists with many different types of interests and expertise led over the next 3 decades to a wealth of new information concerning the biology of the mammary gland and the exceptionally complex composition of HM. Those findings helped to explain why HM is by far the superior nutrition for human infants.

Excisional biopsy (EB) is considered the gold standard for lymphoma diagnosis. Although recent advances in interventional radiology enable sampling with core-needle biopsy (CNB), only few studies evaluated the utility of CNB compared to that of EB.

We analyzed patients with lymphoma who had a diagnostic biopsy at the National Cancer Center Hospital during 2002-2017. We investigated the clinical and pathological characteristics of CNB in 2017.

The proportion of CNB utility in total biopsy procedures had increased from 11 to 48% during the 15 years. In 2017, CNB was opted more frequently than EB for a biopsy of superficial, abdominal, or anterior mediastinal lesions. Only one out of 72 patients who had CNB required re-biopsy with EB because of insufficiency. The incidence of complications was comparable between CNB and EB 2 (4%) cases of minor bleeding with CNB and 1 (8%) case of minor bleeding with EB. The median time from the first visit to biopsy was significantly shorter with CNB (5.5 days) than with EB (15 days).

There is an increasing trend in the utility of CNB. CNB is a less invasive method with shorter time to biopsy and can be considered an alternative to EB.

There is an increasing trend in the utility of CNB. CNB is a less invasive method with shorter time to biopsy and can be considered an alternative to EB.High energy-density supercapacitors (SCs) with long operating life, cost-effective, and competitive cycling performance is attracted great research attention to competing in the requirements of the modern age. However, despite these benefits, SC hampers inadequate rate-capability and structural deterioration, which primarily affects its commercialization. Herein, ultra-thin two-dimensional (2D) ZnCo2O4nanosheets arein situanchored on the conductive surface of nickel foam (denoted as ZCO@NF) by hydrothermal process. The binder-free ZCO@NF is employed as an electrode for SCs and shows impressive charge storage properties. ZCO@NF electrode exhibited a high capacitance of 1250 (750) and 733 F g-1(440 C g-1) at 2.5 and 20 A g-1, respectively, demonstrating the outstanding rate-capability of 58.6% even at 8 times larger current density. Furthermore, the ZCO@NF electrode exhibits admirable capacitance retention of 96.5% after 10 000 cycles. This impressive performance of the ZCO@NF electrode is attributed to the high surface area which gives a short distance for ion/electron transfer, a high conductivity with extensive electroactive cities, and strong structural stability.