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  • Holck Norup posted an update 2 days, 15 hours ago

    Atherosclerosis is a chronic inflammatory event characterized by stiffness and thickening of the vascular walls. In our daily practice, we assume the atherosclerotic potential of the patient by following the total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL) and triglyceride levels (lipid panel). We aimed to understand the relation between the HDL, LDL, cholesterol levels and the atherosclerosis in large vascular structures such as the ascending aorta.

    We have searched for atherosclerosis in the aortic tissue samples from 48 patients. MYCMI6 It is a study in which we examine the correlation of preoperative cholesterol values (HDL, LDL, triglyceride, total cholesterol) by dividing the patients into two groups according to the presence of plaque.

    Forty-three (89.6%) male and 5 (10.4%) female patients between 39 and 81 years of age were included in the study. There was no statistically significant difference between the patients’ preoperative cardiovascular risk assessments. The freerameter to demonstrate atherosclerosis.

    Although echo-guided atrioventricular optimisation (AVO) is standardly performed at rest, this approach may not provide optimal AV synchrony during daily activities.

    The AVO protocol at one of two hospital campuses had been modified to be performed while pacing at an accelerated heart rate. We tested if this approach would improve the yield from AVO compared to the other campus, where AVO was performed at the intrinsic sinus rate.

    Between campuses, no significant differences were seen in demographics, chamber sizes, left ventricular ejection fraction, and diastolic function grade. Those having AVO at C2 were more likely to demonstrate “fusion prone” physiology (36% vs. 9%;

    = 0.006) and were more likely to display either “truncation- or fusion-prone” physiology (58% vs. 27%;

    = 0.007).

    When AVO was performed at an accelerated heart rate, patients with “truncation-prone” or “fusion-prone” physiology were identified more readily.

    When AVO was performed at an accelerated heart rate, patients with “truncation-prone” or “fusion-prone” physiology were identified more readily.

    ST-segment elevation distribution on electrocardiogram (ECG) in patients presenting with ST-elevation myocardial infarction (STEMI) accurately localises the culprit vessel. However, the utility of the ECG changes in localising the coronary culprit territory in the setting of non-ST segment elevation myocardial infarction (NSTEMI) is not well established.

    This study included patients presenting with NSTEMI, who had dynamic non-ST elevation ischaemic changes in one or more ECG leads and underwent percutaneous coronary intervention (PCI) in a single vessel between October 2011 and November 2017 in a single university hospital institution. The accuracy, sensitivity, and specificity of the distribution of ECG changes in localising the culprit vessel were calculated.

    There was a total of 82 patients included in this study, who received PCI to the left anterior descending (LAD), right coronary artery (RCA), and left circumflex (LCX), in 43.9%, 24.4%, and 31.7%, respectively; 51% were male. In this cohort, sensitivity of ECG in localising single-culprit-vessel NSTEMI was 41.5%. The overall accuracy of ECG changes was 50.0%, 72.0%, and 70.0% in LAD, RCA, and LCX distribution, respectively. The sensitivity and specificity were 72.2% and 32.6% in LAD distribution, 20% and 88.7% in RCA distribution, and 15.4% and 82.1% in LCX distributions, respectively.

    Ischaemic non-ST elevation ECG changes had modest accuracy in localising the culprit vessel in patients with PCI-treated NSTEMI. These changes were more sensitive in LAD distribution and more specific in RCA and LCX distributions.

    Ischaemic non-ST elevation ECG changes had modest accuracy in localising the culprit vessel in patients with PCI-treated NSTEMI. These changes were more sensitive in LAD distribution and more specific in RCA and LCX distributions.

    The primary purpose of this work is to study coronavirus disease 2019 (COVID-19) in China and to identify the prognostic characteristics of patients with the highest death risk.

    The statistical methods used to derive the results of this work are the chi-square test and one-way analysis of variance (ANOVA) to examine the characteristics of COVID-19 associated deaths. A multiple logistic regression analysis was used with the odds ratio (OR) to find statistically significant prognostic factors with the highest death risk for this type of disease.

    According to multiple logistic regression analyses, males (OR = 1.68; 95% CI 1.48-1.91) who are over 50 years old (OR = 7.2; 95% CI 1.01-51.6) from Hubei (OR = 7.73; 95% CI 5.71-10.47) have the highest risk of death from this type of disease. Moreover, individuals who are retirees (OR = 2.83; 95% CI 2.47-3.25) and had a Wuhan-related exposure (OR = 2.17; 95% CI 1.68-2.79) have two times higher risk of death from COVID-19, while the risk is thirteen times higher with the comorbid condition “cardiovascular disease” (OR = 13.6; 95% CI 10.3-17.9).

    The results of this study describe for the first time the importance of cardiovascular disease as a primary prognostic risk factor for death from coronavirus disease 2019.

    The results of this study describe for the first time the importance of cardiovascular disease as a primary prognostic risk factor for death from coronavirus disease 2019.Cranial nerve III palsy, also known as oculomotor nerve palsy, may result from various causes; however, the etiology remains unknown in some instances. The aim of this case report is to present the authors’ experience with two cases of idiopathic cranial nerve III palsy, together with a review of the literature. Case 1 is a 78-year-old woman and case 2 is a 75-year-old man, both having no history of trauma and no vascular risk factors. They presented to the authors’ hospital with diplopia and palpebral ptosis and were diagnosed with idiopathic unilateral cranial nerve III palsy. They received oral steroids for treatment. One patient recovered completely within 3 months, while the other patient did not recover regardless of long-term follow-up. Idiopathic cranial nerve III palsy can occur in otherwise healthy individuals and often recover in several months. Careful examinations to rule out other causes and then steroid treatment should be considered after early diagnosis.