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Incidence of viral pneumonia has been reported in several patients diagnosed with COVID-19. The infection has also been linked to the development of inflammatory syndromes and related clinical manifestations.

The present study discusses four cases of COVID infection showing varying clinical features. The post-COVID inflammation syndrome was associated with non-specific inflammation and post viral arthritis in three cases. One other subject had vasculitis leading to central retinal artery occlusion.

As the number of cases of COVID-19 cases has been increasing globally, it is advisable that physicians consider the possibility of post-COVID manifestations while examining patients with non-specific inflammation. A short course of NSAIDs and hydroxychloroquine regimen has been found to be beneficial for alleviating symptoms, and in rare cases with organ threatening inflammation, steroids may be required.

As the number of cases of COVID-19 cases has been increasing globally, it is advisable that physicians consider the possibility of post-COVID manifestations while examining patients with non-specific inflammation. A short course of NSAIDs and hydroxychloroquine regimen has been found to be beneficial for alleviating symptoms, and in rare cases with organ threatening inflammation, steroids may be required.

Nearly three months after its first recorded case, the progression of the coronavirus disease (COVID-19) pandemic has been slow in India so far, with relatively low number of cases and deaths. The behavior of the general public will probably have the most important bearing on the course of the disease over the next few months in India. We aim to study the awareness, attitudes and perceptions of COVID-19 among the adult Indian population.

A cross-sectional online survey was conducted using the ‘Google Survey Forms’ between 29th March and 14th April 2020 and distributed through email and various social media groups.

There were 1502 respondents, majority were male (56.7%), between 30-49 years (47.7%). 90% of the respondents had either an undergraduate or postgraduate degree, with a third of them being in the healthcare sector (34.6%). Most of the respondents were aware of the common symptoms of COVID-19, but worryingly only a third (31%) were aware of the risk of spread from infected asymptomatic individuals, which is a major concern in India. Majority were aware of the modes of virus transmission, but only two-thirds (68.6%) were aware of the safe physical distance (6 feet) for maintain social distancing. A majority of respondents were appreciative of the government interventions in containing the virus spread and would support further extension of lockdown if necessary.

Despite limitations of generalizability, this survey has identified areas which the public health authorities need to target in future information campaigns.

Despite limitations of generalizability, this survey has identified areas which the public health authorities need to target in future information campaigns.

A virtual registry study evaluating real world evidence on physicians’ use of prophylactic regimens for protection against SARS-CoV-2. This paper summarizes the interim results.

Asymptomatic physicians at risk of acquiring SARS-CoV-2 responded to online questions at baseline and 7 weeks post-baseline. Baseline data included demographics, prophylaxis regimen (including “no prophylaxis”) and start date. Participants who provided complete week-7 data (information on type of health facility [COVID/Non-COVID], number of presumed/confirmed cases exposed to, PPE use, SARS-CoV-2 testing and symptoms, regimen adherence and intercurrent illness) comprised the Completer population. Limited data (regimen adherence, SARS-CoV-2 testing) was collected for participants who failed to provide complete week7 data. Those providing limited/complete information comprised the Evaluable population.

Of 369 enrolled participants, 182 (mean age 42±11.05 years) comprised the Evaluable population. They showed a male preponderance (67.6%). Practitioners from Maharashtra (59.9%) and specialties of Pediatrics, Internal Medicine, Anesthesiology and Critical Care (63.2%) accounted for the majority. ICMR’s HCQ prophylaxis regimen was initiated by 125 (68.7%) participants with 31 (17%) initiating ‘No prophylaxis’. The highest adherence was for the ICMRregimen (87.2%). In the Completer population comprising 150 participants, 87 were exposed to presumed (81) and/or confirmed cases (60). Most exposures to confirmed cases (49, 81.7%) were high-risk. PPE use was generally high (75-100%). Most participants (94.7%) did not report an AE. The proportions with an AE was similar with ICMR regimen (5.9%) and no prophylaxis (6.5%).

Physicians in India preferred ICMR’s HCQ regimen. The regimen appears to be safe and associated with a high level of adherence.

Physicians in India preferred ICMR’s HCQ regimen. The regimen appears to be safe and associated with a high level of adherence.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is rapidly spreading in India and across the world. Healthcare workers (HCWs) are at increased risk of contracting COVID-19 due to direct or indirect exposure to COVID-19 patients, and require special attention. Limited information is available about its effect in HCWs. Secondary transmission from HCWs is a possibility among patients, family members, and the community. NBQX in vivo Therefore, it is important to investigate the infection risk of HCWs and the clinical characteristics of affected cases and possible source of infection with exposure details.

The aim of this study is to analyze the medical records of HCWs with COVID-19 retrospectively and carry out the analysis of the data of HCWs with COVID-19 at TNMC and BYL Nair Charitable Hospital (NH, COVID-19 Hospital) in Mumbai.

Interim analysis was carried out for the data collected from 6th April to 20th August 2020. Total 3711 HCWs (frontline, 74.32%, non-frontline, 25.68%) are working at NHgion, and at Maharashtra state level.This study aimed to evaluate the impact of errorless and errorful learning, on acquisition of root canal hand-instrumentation skills. Dental students prepared standardised canals of different diameters and curvatures. Learning involved minimising (errorless n = 21) or maximising errors (errorful n = 21). Students who had completed accredited pre-clinical activities provided comparative data (n = 17). During testing, the distal canal of a plastic mandibular molar was prepared, first as a single task and then under multi-tasking conditions. Performance was assessed by preparation accuracy and time. Differences were assessed using anova (P less then 0.05). Performance in the experimental groups was similar during learning. When multi-tasking, errorful learners showed a deterioration in preparation accuracy (P less then 0.05). In contrast, preparation accuracy and completion times for the errorless and comparative groups remained stable when multi-tasking. Errorless learning resulted in stable performance under multi-tasking conditions. Investigation of alternative approaches to learning motor skills in dentistry is warranted as such approaches may provide better outcomes, especially under demanding conditions.

Molecular imaging with novel radiotracers is changing the treatment landscape in prostate cancer (PCa). Currently, standard of care includes either conventional and molecular imaging at time of biochemical recurrence (BCR). This study evaluated the determinants of and cost associated with utilization of molecular imaging for BCR PCa.

This is a retrospective observational cohort study among men with BCR PCa from June 2018 to May 2019. Multivariate logistic regression models were employed to analyze the primary outcome receipt of molecular imaging (e.g. Fluciclovine PET and Prostate Specific Membrane Antigen PET) as part of diagnostic work-up for BCR PCa. Multivariate linear regression models were used to analyze the secondary outcome overall healthcare cost within a 1-year time frame.

The study sample included 234 patients; 79.1% White, 2.1% Black, 8.5% Asian/Pacific Islander, and 10.3% Other. The majority were 55years or older (97.9%) and publicly insured (74.8%). Analysis indicated a one-unit reduction in PSA is associated with 1.3 times higher likelihood of receiving molecular imaging (p<0.01). Analysis found that privately insured patients were associated with approximately $500,000 more in hospital reimbursement (p<0.01) as compared to the publicly insured. Additionally, a one-unit increase in PSA is associated with $6254 increase in hospital reimbursement or an increase in total payments by 2.1% (p<0.05).

Higher PSA was associated with lower likelihood for molecular imaging and higher cost in a one-year time frame. Higher cost was also associated with private insurance, but there was no clear relationship between insurance type and imaging type.

Higher PSA was associated with lower likelihood for molecular imaging and higher cost in a one-year time frame. Higher cost was also associated with private insurance, but there was no clear relationship between insurance type and imaging type.

Narcolepsy type 1 (NT1) is a chronic rare hypersomnia of central origin requiring a combination of behavioral and pharmacological treatments. During the coronavirus disease 2019 (COVID-19) pandemic, in Italy the population was forced into a lockdown. With this study, we aimed to describe the lockdown impact on NT1 symptom management, according to different patients’ working schedule.

In the period between 10 April and 15 May 2020, we performed routine follow-up visits by telephone (as recommended during the COVID-19 emergency) to 50 patients >18years old (40% males) under stable long-term treatment. We divided patients into three groups unchanged working schedule, forced working/studying at home, and those who lost their job (“lost occupation”). Current sleep-wake habit and symptom severity were compared with prelockdown assessment (six months before) in the three patient groups.

At assessment, 20, 22, and eight patients belonged to the unchanged, working/studying at home, and lost occupation groups, respectively. While in the lost occupation group, there were no significant differences compared with prepandemic assessment, the patients with unchanged schedules reported more nocturnal awakenings, and NT1 patients working/studying at home showed an extension of nocturnal sleep time, more frequent daytime napping, improvement of daytime sleepiness, and a significant increase in their body mass index. Sleep-related paralysis/hallucinations, automatic behaviors, cataplexy, and disturbed nocturnal sleep did not differ.

Narcolepsy type 1 patients working/studying at home intensified behavioral interventions (increased nocturnal sleep time and daytime napping) and ameliorated daytime sleepiness despite presenting with a slight, but significant, increase of weight.

Narcolepsy type 1 patients working/studying at home intensified behavioral interventions (increased nocturnal sleep time and daytime napping) and ameliorated daytime sleepiness despite presenting with a slight, but significant, increase of weight.