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Background The purpose of this research was to investigate the relationship between Menopause Specific Quality of Life (MENQOL), Perceived Social Support (PSS) and factors associated with MENQOL among a group of Iranian Postmenopausal women in 2018. Methods In this cross-sectional study 410 of Postmenopausal Iranian women in Neyshabur are…[Read more]

Ventricular function in elderly patients with aortic stenosis is impeded both by restricted aortic flow and arterial stiffening. A number of patients continue to have exertional intolerance after relief of aortic valvular obstruction due to unrecognized ventriculo-arterial coupling mismatch.

Quantification of valvulo-arterial load (VAL),…[Read more]

The overall results reveal that EDTA-EMR is a promising adsorbent ascribed by its low cost, good recyclability and excellent adsorption capacity.Microplastics pollution has emerged as one of the top-ranked global environmental issues, receiving worldwide attention in recent years. However, knowledge about the detrimental effects of microplastics…[Read more]

47, p<0.001).

There is a substantial proportion of major trauma within e-scooter injuries. Modifiable risk factors for hospital admission include use of head protection and substance use while riding e-scooters.

There is a substantial proportion of major trauma within e-scooter injuries. Modifiable risk factors for hospital admission…[Read more]

Margin-negative (R0) resection is the only potentially curative treatment for patients with pancreatic ductal adenocarcinoma (PDAC). Pre-operative multi-agent chemotherapy alone (MAC) or MAC followed by pre-operative radiotherapy (MAC+RT) may be used to improve resectability and potentially survival. However, the optimal pre-operative regimen is…[Read more]

The results show good agreement with an average error of 1% for the simulation data and under 4% for the experimental data compared to reference measurements.Decapitation is common in horticulture for altering plant architecture. The decapitation of chrysanthemum plants breaks apical dominance and leads to more flowers on lateral branches,…[Read more]

uctural failures that are leading to unacceptable and substandard maternal and infant outcomes.The regulatory community is transitioning to the use of nonanimal methods for dermal sensitization assessments; however, some in vitro assays have limitations in their domain of applicability depending on the properties of chemicals being tested. This…[Read more]

Utilizing historical clinical datasets to guide future treatment choices is beneficial for patients and physicians. Machine learning and feature selection algorithms (namely, Fisher’s discriminant ratio, Kruskal-Wallis’ analysis, and Relief-F) have been combined in this research to analyse a SEER database containing clinical features from…[Read more]

70, and the correlations between genomic-predicted own phenotype and GCA were similar to the observed correlations. Our results suggest that genome-assisted parental selection (GAPS) is a credible alternative to phenotypic parental selection, so could help reduce the generation interval to allow faster accumulation of favourable alleles from donor…[Read more]

This article has an associated ‘The people behind the papers’ interview.

The coronavirus disease pandemic has disproportionately affected poor and racial/ethnic minority individuals and communities, especially Indigenous Peoples. The object of this study is to understand the spatially varying associations between socioeconomic disadvantages…[Read more]

he patient can vary from early prevention, using single or a combination of external devices such as optical devices and various forms of medical treatments, surgical and other. Although the visual system is affected by other senses, vision also affects other systems in the body. The objective here is to isolate specifically visual-related changes…[Read more]

ofen axetil combined with ropivacaine for bilateral transversus abdominis plane block has a significant analgesic effect on patients after gynecologic surgery. The mechanism may be due to the fact that nonsteroidal analgesics combined with nerve block further reduce the inflammatory factors in the body, which proves the superiority of multimodal…[Read more]

In recent years, South Korea has become more concerned about a dignified death and the ‘well-dying’ law has been enacted. Oncology nurses’ perceptions of death are crucial in maintaining dying patients’ sense of dignity; fostering their physical, mental, and spiritual quality of life; and ensuring that they die a comfortable death. This study…[Read more]

gh detailed visual examination appears to be effective in identifying, previous systematic reviews have not evaluated a relevant number of studies and they did not evaluate the accuracy of the clinical examination.

We aimed to compare oral and pathogenic microorganisms in bloodstream infections (BSIs) in allogeneic hematopoietic stem cell…[Read more]

The results obtained by the cell deconvolution approach are supported by the analysis performed by WGCNA. Our report describes the largest differential gene expression profiling in peripheral blood of ASD subjects and controls conducted by RNASeq. The observed signatures are consistent with the hypothesis of immune alterations in autism and an…[Read more]

l native T1 values. Level of evidence 3 TECHNICAL EFFICACY STAGE 2.Background Malnutrition is a risk factor for impaired functionality and independence. For optimal treatment of malnourished older adults (OA), close collaboration and communication between all stakeholders involved (OA, their caregivers and health-care and welfare professionals) is…[Read more]

The increasing rate of academic plagiarism is a social problem that engages institutions and publishers. Plagiarists try to mislead the plagiarism detection system using synonyms and inverted word order. Numerous algorithms tried to overcome these problems using structural and semantic detection. However, most of them focus on overcoming some…[Read more]

We succeeded in monitoring the membrane order in the Golgi apparatus, Mitochondria, and plasma membrane in the samein-vivocell and quantitatively comparing them. The phasor-based multi-harmonic unmixing method can help expand the outreach of HSI and democratize its use by the community for it does not require specialized knowledge.To predict the…[Read more]

apoptosis was mediated by AKT signaling, and subsequently modulated via the mitochondria‑dependent signaling pathway. Therefore, the results suggested that suppression of AKT/mTOR activity triggered autophagy in the HT‑29/5FUR cell line. In summary, the results indicated that MJ‑33 inhibited HT‑29/5FUR cell viability, and induced apoptosis and aut…[Read more]

These inductions were abolished by NLRP3 deficiency in DCs, suggesting that NLRP3 in MLES-treated DCs plays a role in promoting the Th2 and Treg response. selleck kinase inhibitor Taken together, we identified for the first time the involvement of NLRP3 in host defences against T. spiralis.

Synovitis-associated pain is mediated by inflammatory…[Read more]